Kalantzis D. DVM, Intern at the Department of Anaesthesia and Critical care, Companion Animal Clinic, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, Greece | Tzortzi I. DVM, MSc, PhD Candidate, Companion Animal Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece | Lorida O. DVM, PhD Candidate, Companion Animal Clinic, Department of Veterinary Medicine, Aristotle University of Thessaloniki, Greece | Papageorgiou V. DVM, MSc, PhD candidate, Companion Animal Clinic, School of Veterinary Medicine, Aristotle University of Thessaloniki | Papadimitriou S. DVM, DDS, PhD, Professor, Companion Animal Clinic, Department of Veterinary Medicine, Aristotle University of Thessaloniki, Greece | Kazakos G. DVM, PhD, Professor of Surgery and Anesthesiology-Critical Care, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece
Introduction
The use of acetylpromazine(ACP) is preferred as pre-anesthetic medication in dental procedures since it does not affect the color of the mucous membrane of the oral cavity. However, ACP provokes vasodilation resulting in hypotension, and thus, these patients should be hemodynamically supported.
Materials and methods
This study included 40 cats that underwent dental procedures. ACP 0.02 mg/kg and butorphanol 0.5 mg/ kg were administered intramuscularly (IM) in all cases for sedation.
Mean arterial pressure (MAP) was measured intraoperatively with the oscillometric method. In case of hypotension (MAP < 60mmHg), dopamine (Group D) or noradrenaline (Group N) were administered in a constant rate infusion (CRI).
Results
All patients developed hypotension intraoperatively. In group N (n = 10), the efficacious dose in restoring hypotension ranged from 0.1 to 0.6 μg/ kg/min, and the corresponding time was 7.5 minutes (median). In group D (n = 27), the efficacious dose ranged from 7 to 14 μg/kg/min, and the corresponding time was 10 minutes (median). Moreover, the administration of dopamine increased heart rate by 15.7%.
Conclusions
The hypotension related to the administration of ACP can be resolved either by administering dopamine or noradrenaline, emphasizing that dopamine requires more time to restore hypotension compared to noradrenaline.
