Sarpekidou E. DVM, PhD student, Companion Animal Clinic, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece
Koura M. DVM, Intern at the Department of Anaesthesia and Critical care, Companion Animal Clinic, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki
Kazakos G. DVM, PhD, Associate Professor, Companion Animal Clinic, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece
Pavlidou K. DVM, PhD, Post Doc Researcher, Companion Animal Clinic, Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece
Dogs suffering from compressive myelopathies show differences in the intensity of pain, depending on the location. The aim of the study is to compare the dose of propofol needed for intubation of dogs with cervical syndrome to those needed for dogs with thoracolumbar syndrome.
Materials and methods
In this clinical study that consisted of 41 dogs, ASA 2, 21 with thoracolumbar syndrome and 20 with cervical syndrome, dexmedetomidine 180 μgm- 2 was administered intramuscular for sedation followed by intravenous injection of propofol for anesthesia induction. Anesthesia was maintained with isoflurane in 100% oxygen. Pain scoring was conducted in every dog preanaesthetically using the Glasgow pain scale.
Dogs suffering from cervical syndrome needed a statistically significant higher (p<0.001) dose of propofol for induction (3.1±1.071 mgkg-1 [mean ± standard deviation]) than those suffering from thoracolumbar syndrome (1.7±0.463mgkg-1). Dogs with cervical syndrome had also statistically higher Glasgow Pain Scale score (GPS) (13.2/24) than those with thoracolumbar syndrome (8.4/24) (p<0.001). In addition, there was a positive linear correlation between the intensity of pain (Glasgow pain scale score) and the propofol dose (p<0.001).
Results suggest a positive correlation of pain with the amount of propofol required for intubation. Further studies with larger sample size are warrant.
- Klinck MP and Troncy E (2016) Chapter 8 The physiology and Pathophysiology of pain, in BSAVA Manual of Canine and Feline Anaesthesia and Analgesia, third edition. Edited by Tanya Duke-Novakovski, Marieke de Vries and Chris Seymour, 3rd edn, pp. 97-112, British Small Animal Veterinary Association, Gloucester.
- Züger L et al. (2018) Differences in Epidural Pathology between Cervical and Thoracolumbar Intervertebral Disk Extrusions in Dogs, Jour- nal of Veterinary Internal Medicine 32(1), pp. 305–313.