Moraiti K. PhD Student, Clinic of Medicine, Faculty of Veterinary Science, University of Thessaly, Karditsa, Greece
Del Baldo F. Junior Assistant Professor, Department of Veterinary Medical Sciences, University of Bologna, Italy
Fracassi F. Associate Professor, Department of Veterinary Medical Sciences, University of Bologna, Italy
Vaggeli V. Undergraduate Student, Faculty of Veterinary Science, University of Thessaly, Karditsa, Greece
Steiner J.M. Regents Professor and University Distinguished Professor, GI Lab, Texas A&M University, College Station, Texas, USA
Xenoulis P. Associate Professor, Clinic of Medicine, Faculty of Veterinary Science, University of Thessaly, Karditsa, Greece and Adjunct Assistant Professor, Texas A&M University, College Station, Texas, USA
Introduction
Diabetes mellitus (DM) is the most common disorder of the endocrine pancreas, whereas pancreatitis and exocrine pancreatic insufficiency (EPI) are the disorders of the exocrine pancreas. The aim of this study was to describe the prevalence of pancreatitis and EPI in dogs with DM.
Materials and methods
A total of 51 dogs were enrolled into this study. Serum samples were available from the initial presentation as well as from reexaminations. Serum Spec cPL and cTLI concentrations were measured to screen for pancreatitis and EPI, respectively.
Results
Serum Spec cPL was indicative of pancreatitis (> 400 μg/L) in 22/51 (43%) dogs and cTLI was indicative of EPI (< 2.5 μg/L) in 3/51 (6%) dogs. Serum Spec cPL and cTLI were within the grey zone in 15/51 (29%) and 2/51 (4%) dogs with DM, respectively.
Conclusions
The prevalence of pancreatitis in dogs with DM is high, while a smaller percentage of dogs develop EPI.
References
- Hamilton K, O’Kell AL, Gilor Chen (2021) Serum trypsin-like immunoreactivity in dogs with diabetes mellitus. J Vet Intern Med 35, 17131719.
- Xenoulis PG, Steiner JM (2012) Canine and feline pancreatic lipase immunoreactivity. Vet Clin Pathol 41(3), 312-24.
- Xenoulis PG (2015) Diagnosis of pancreatitis in dogs and cats. J Small Anim Pract 56(1), 13-26.
- Bolton TA, Cook A, Steiner JM, et al (2016) Pancreatic lipase immunoreactivity in serum of dogs with diabetic ketoacidosis. J Vet Intern Med 30(4), 958-963.
